What are the key barriers to the uptake of doxycycline postexposure prophylaxis (DoxyPEP) for STI prevention among populations with elevated exposure risk for bacterial STIs This document outlines the inclusion

Research Question: What are the key barriers to the uptake of doxycycline postexposure prophylaxis (DoxyPEP) for STI prevention among populations with elevated exposure risk for bacterial STIs This document outlines the inclusion and exdusion criteria for a literature review focused on the barriers to the uptake of doxycycline post-exposure prophylaxis (DoxyPEP) for STI prevention among key populations. These criteria are used to guide article selection and maintain consistency and rigor throughout the review process. Category Population Intervention/Exposure Focus on Barriers Study Type Geographic Location Language Publication Date Duplication Inclusion Criteria Key populations disproportionately affected by bacterial STIs (e.g., MSM, transgender individuals, sex workers, individuals with previous STIs) Doxycycline as postexposure prophylaxis (PEP) for STI prevention Articles discussing barriers to DoxyPEP uptake (e.g., stigma, access, provider concerns, resistance, policy) Empirical studies, systematic reviews, metaanalyses, or reputable grey literature High-income countries (e.g., U.S., Canada, Western Europe, Australia) English 2018-2025 Exclusion Criteria Gen